Nitrazepam has been related to serious hepatic Problems, comparable to other nitrobenzodiazepines. Nitrobenzodiazepines including nitrazepam, nimetazepam, flunitrazepam, and clonazepam are more harmful on the liver than other benzodiazepines as They are really metabolically activated by CYP3A4 which may result in cytotoxicity.Keep to the actual dos